I'm in my 50's, single and looking to move to the philly area.

Personally, I prefer Whitman or Pennsport area or even Lower Moyamensing. They are close to public transportation, reasonably priced, easy to commute by car if needed, and have lots of amenities like big grocery stores, dry cleaning, etc. but also local mom and pop shops. Walkable to bars and nightlife, easy distance to Center City or Passyunk from public transport, and still quiet and safe.