Would you recommend the Flatiron neighborhood in New York City for singles?

I guess, close to some great nightlife neighborhoods.

It's ok. There are a few spots, like Lily's, Rye House and Raine's Law Room are all great. But, they're definitely all an after work crowd. There isn't a lot going on late at night here and the restaurant selection is pretty paltry. Luckily, Flatiron is really central. Chelsea, Greenwich and the East Village are all in walking distance so you wouldn't be stuck there every night just because you lived there.